Intra-articular Corticosteroid versus Hyaluronic injections in the treatment of Patellofemoral Osteoarthritis of the Knee. A comparative double blinded randomized controlled trial.

Phase 3

Completed

• Conditions: patellofemoral osteoarthritis; PFOA

• Registration Number: TCTR20200709009
• Lead Sponsor: Faculty of medicine,Thammasart University.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-07-09
• Study Completion: 2022-07-10
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. Patient diagnosed with Isolated Patellofemoral osteoarthritis
(Diagnostic criteria: Patient having anterior knee pain while getting up and walking upstairs, physical examination shows tenderness at the patellofemoral joint line, patellar grinding test positive. And Knee Lateral or patella skyline X-RAY/MRI consists of OA change of the Patellofemoral joint.

2. Persistent anterior knee pain with VAS more than 30/100mm despite the conservative treatment for 3 months.

3. Age 35-80 years.

4. Understandable, Co-operate with treatment and follow-up protocol.

Exclusion Criteria

1. Patients with moderate to severe tibiofemoral osteoarthritis. (defined as having the radiographic osteoarthritic change with Kellegren and Lawrence classification of grade 3 or 4 of the tibiofemoral joint.)

2. Patient with abnormal Knee Alignment and Knee deformities.

3. Patient with Knee and Patella Instability.

4. Patient with inflammatory joint disease eg. RA, Crystal induced arthritis.

5. Patient with Post Traumatic patellofemoral osteoarthritis.

6. Patient receiving HA or Corticosteroid injection or previous knee surgery for the past 6 months.

7. Patient allergic to HA or Corticosteroid.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
VAS pain 100mm 48hr, 72hr, 1wk, 2wks, 4wks, 12wks, 24wks. asking the patient to fill the form with the Visual Analog Scale 100mm

Secondary Outcome Measures

Name	Time	Method
Kujala score 48hr, 72hr, 1wk, 2wks, 4wks, 12wks, 24wks. using Thai version Kujala score ,Adverse event. 48hr, 72hr, 1wk, 2wks, 4wks, 12wks, 24wks pain, fever, aleergic reaction, infection,Pain during injection 0hr (during injection) VAS pain 100mm