The effect of regulating the flow rate of cardiopulmonary bypass pump based on lean body mass index on mixed venous blood oxygen and arterial blood lactat level among patients with abnormal range of body mass index
- Conditions
- Heart disease.Atherosclerotic cardiovascular disease, so described
- Registration Number
- IRCT2017012932276N1
- Lead Sponsor
- iran univercity of medical science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 152
1? Older than 18 years old 2? body mass index of between 25-35 3?open heart surgery with the use of cardiopulmonary bypass 4?not having disorder in kidney, lung, liver and cerebral and treatment-resistant hypertension 5, left ventricular ejection fraction more than 30% 6? patients with bilateral carotid artery stenosis greater than 50% or unilateral carotid stenosis greater than 70% 7,patients elective open heart surgery
exclusion criteria from the study:
1 , any event that affect the normal process of open heart surgery include cardiopulmonary bypass requirement though surgery, persistent decline of blood pressure through cardiopulmonary bypass that not respond to Inotropic drug 2, death 3, aortic clamping time over 100 minutes 4, temperature reduction below 28 degree during operation for any reason the surgeon decide to catch a lower temperature than 28 degree
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method On mixed venous oxygen saturation. Timepoint: after anesthesia,during cardiiopulmonary bypass,after cardiopulmonary bypass. Method of measurement: content of each gas in arterial blood Under the pressure of eac gas.;Arterial blood lactate. Timepoint: after anesthesia,during cardiiopulmonary bypass,after cardiopulmonary bypass. Method of measurement: arterial blood sample.
- Secondary Outcome Measures
Name Time Method O2 consumption. Timepoint: during cardiopulmonary bypass. Method of measurement: content of each gas in venous blood Under the pressure of eac gas and pump flow rate.