Physiologic changes of cardiocirculatory parameters in normobaric hypoxia

• Conditions: Mountain sicknessHealthy volunteers; T70.2; Other and unspecified effects of high altitude

• Registration Number: DRKS00005459
• Lead Sponsor: niversitätsklinikum Jena

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2013-11-21
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Male
• Target Recruitment: 12

Inclusion Criteria

Willingness to participate

Exclusion Criteria

Signifikant morbidity in the past

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
3D-Echokardiography (Torsion and Twist of left and right ventricle, PA-pressure, Vitien. Measurements Basleline and 5500m). Laser-doppler (flow profiles, Fourier-Analysis: Baseline and 5500m), Laboratory values (blood count, Cytokines, BNP, Troponin, thrombocyte function; baseline, 4000 and 5500m), Count of circulating regulatory T-cells (Baseline, 5500m), dendritic cells (Baseline, 5500m), <br>Metabolomics (Baseline, 4000m, 5500m),<br>Protein expression of erythrocytes (Basleline, 4000m, 5500m). Retinal vessel analysis (Baseline, 5500m).