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临床试验/NCT05406843
NCT05406843已完成不适用

Postoperative Cognitive Dysfunction in Participants Undergoing Open Heart Surgery

Kocaeli University1 个研究点 分布在 1 个国家目标入组 140 人开始时间: 2020年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
140
试验地点
1
主要终点
Evaluation of postoperative cognitive functions in participants undergoing open heart surgery.

研究概览

简要总结

To determine the rate of Postoperative Cognitive Dysfunction (POCD) in the early and late postoperative periods by comparing the preop and postop period mini mental status tests in participants undergoing open heart surgery, and to compare the results of the investgators clinic with the world literature.

详细描述

Postoperative delirium (POD) and Cognitive Dysfunction (POCD) are changes in mental status, especially in the geriatric surgery population.Unlike other forms of delirium, POD results in early full recovery.Postoperative Cognitive Dysfunction (POCD) is more difficult to define and implies temporal consciousness impairment associated with surgery.

While the diagnosis of delirium requires the detection of symptoms, the diagnosis of POCD requires preoperative neuropsychological testing and determining how much reduction will mean cognitive dysfunction. Postoperative delirium management is complex and requires multiple strategies. Methods of treating and preventing POCD are still uncertain.It is known that POCD is most commonly seen in patients undergoing open heart surgery.In this study, the investigators aim is to evaluate whether there is any change in cognitive status in the postoperative period compared to the preoperative period of participants who will undergo open heart surgery due to valve pathology or coronary stenosis.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 18-75 age
  • American Society of Anesthesiologists (ASA) II-III

排除标准

  • Patients who died within 48 hours after the operation

结局指标

主要结局

Evaluation of postoperative cognitive functions in participants undergoing open heart surgery.

时间窗: 1 year

The aim is to understand whether there is a loss of cognitive functions in the postoperative period, according to the preoperative periods, by testing the participants with open heart surgery on the 3rd day, 7th day, and 2nd month after the surgery.

次要结局

  • Comparison with the literature.(1 year)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Huri Yeşildal

Assistant

Kocaeli University

研究点 (1)

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