Effects of artificial light on the processing of stimuli during wakefulness and sleep
- Conditions
- healthy volunteers
- Registration Number
- DRKS00023602
- Lead Sponsor
- niversität Basel
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting stopped after recruiting started
- Sex
- All
- Target Recruitment
- 30
• Age: 18-30 years
• Body Mass Index: 18.5-24.9 (i.e. normal weight according to WHO criteria)
• Informed consent as documented by signature of the participant
• Previous enrolment in the study’s project part
• Investigator’s family members, employees or other dependent persons
• Left-handedness
• Pregnancy
• Hearing difficulties/ a hearing aid
• Chronic or debilitating medical conditions
• Drug use
• Shift work < 3 months prior to beginning of the study
• Transmeridian travel (> 2 time zones) < 1 month prior to beginning of the study
• Extreme chronotype (Munich Chronotype Questionnaire [MCTQ; 21] <2 or >7)
• Short and long sleep duration (subjective sleep duration on workdays outside 6-10h according to the MCTQ)
Exclusion criteria due to study requirements
• Inability to understand and/or follow procedures
• Mother tongue other than the project language (German)
• Non-adherence to sleep/wake times during the ambulatory part
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcomes are EEG-derived parameters of event-related oscillatory activity (event-related de-/synchronisation in the 1-15 Hz range) as well as event-related potentials (mismatch negativity, P3, K-complex-like responses). The outcomes are assessed using an acoustic stimulation paradigm (i.e., an oddball task) participants undergo during the light exposure in the evening as well as during the whole night.
- Secondary Outcome Measures
Name Time Method Secondary outcomes are sleep quality indexes, salivary melatonin levels as well as the spectral composition of the EEG signal during resting-state recordings (wakefulness) and stimulation-free periods during sleep. Moreover, also subjective sleepiness (assessed by a questionnaire) is a secondary outcome.