The Beneficial Effects of Intradialytic Parenteral Nutrition on Nutritional Status among Patients Receiving Hemodialysis: A Randomized Controlled Trial

Completed

• Conditions: ndernutrition hemodialysis patients; End stage renal disease; Hemodialysis; Omega-3; Fish oil; Intradialytic parenteral nutrition

• Registration Number: TCTR20191223006
• Lead Sponsor: Grant for research, Faculty of medicine, Chulalongkorn University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-12-23
• Study Completion: 2020-08-03
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 35

Inclusion Criteria

1. Patients with maintenance chronic hemodialysis > 3 month
2. Patients who can't tolerate oral nutrition supplement
3. Patients who have spontaneous energy intake > 20 kcal/kg/day and protein > 0.8 g/kg/day after conventional dietary counseling
4. With 2/4 of
Serum albumin < 3.5 g/dL
Serum prealbimin < 30 mg/dL
7-point SGA category B
MIS >= 5

Exclusion Criteria

1. Serum triglyceride > 300 mg/dL
2. Blood sugar > 300 mg/dL
3. Pregnancy or lactation
4. Advanced stage malignancy
5. Current inflammation or infection such as CRBSI, tuberculosis
6. Having anti-inflammatory drugs
7. Cirrhosis
8. AIDs

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum albumin 0, 3, 6 months Blood sample

Secondary Outcome Measures

Name	Time	Method
Serum prealbumin 0, 3, 6 months Blood sample,Somatic protein 0, 3, 6 months BIA, BCM, handgrip strength test,MIS 0, 3, 6 months Assess by dietician,SGA 7-point 0, 3, 6 months Assess by dietician,IL-6 0, 3, 6 months Blood sample,hsCRP 0, 3, 6 months Blood sample,Acyl ghrelin 0, 3, 6 months Blood sample,Leptin 0, 3, 6 months Blood sample