Comparison of Early Operative Treatment (12 h) and 48 h Conservative Treatment in Acute Small Bowel Obstruction
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Small Bowel Obstruction
- Sponsor
- Pirogov Russian National Research Medical University
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- Quantity of patients with obstruction release after conservative treatment
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
This study will compare the results of early surgery after 12 h conservative treatment and 48 h conservative treatment of adhesive small bowel obstruction.
Detailed Description
At the admission patients undergo abdomen x-ray, general and biochemical blood test and computer tomography (CT). After exclusion of indications for an emergency operation, patients are given a water-soluble contrast. Conservative treatment is carring out to 12 hours from admission. All patients with resolution of small bowel obstruction in 12 hours will be excluded from the research. Criteria for obstruction release of conservative treatment 1. No pain 2. Appearance of gas in the colon 3. Decrease of bloating 4. Contrast in the colon. After that, if obstruction is not resolved, randomization is performed. First group undergo surgery. Second group undergo conservative treatment with water-soluble contrast evaluation until 48 hours. In the second group surgery is performed if the conservative treatment is not effective. The results of early and late surgery and the results of conservative treatment in groups will be compared.
Investigators
Alexander E. Tyagunov
MD. Prof
Pirogov Russian National Research Medical University
Eligibility Criteria
Inclusion Criteria
- •Patients with adhesive small bowel obstruction
Exclusion Criteria
- •Early postoperative small bowel obstruction Irreducible hernia Strangulation or peritonitis symptoms Impairment of consciousness Unstable hemodynamics
Outcomes
Primary Outcomes
Quantity of patients with obstruction release after conservative treatment
Time Frame: in the 2nd group - 48 hours
No of patients with success of conservative treatment
Secondary Outcomes
- Readmission rate in conservative treatment and surgery(12 months)
- 30 days mortality(30 days)
- Complications rate(30 days)
- Quantity of bowel resection(156 hours)