Is Fast Reversal and Early Surgery (Within 24 h) in Patients on Warfarin Medication With Trochanteric Hip Fractures Safe: A Case-control Study

Karolinska Institutet1 site in 1 country198 target enrollmentOctober 1, 2017

ConditionsTrochanteric Hip Fractures Warfarin Medication Early Surgery

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Trochanteric Hip Fractures
Sponsor: Karolinska Institutet
Enrollment: 198
Locations: 1
Primary Endpoint: Transfusion rates
Status: Completed
Last Updated: 5 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

A retrospective case-control study. To evaluate if early surgery within 24hours of troch or subtrochanteric hip fractures using intramedullary nailing is safe in patients on warfarin treatment after fast reversal of the warfarin effect

Registry

clinicaltrials.gov

Start Date

October 1, 2017

End Date

June 26, 2018

Last Updated

5 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Karolinska Institutet

Responsible Party

Principal Investigator

Leif Mattisson

Senior Consultant Orthopaedic Surgeon MD.,Ph.D.

Karolinska Institutet

Eligibility Criteria

Inclusion Criteria

Not provided

Exclusion Criteria

•Pathological fracture
•Late presentation to the hospital
•Other injuries

Outcomes

Primary Outcomes

Transfusion rates

Time Frame: 2-4 days after the surgery

Transfusion rate (n)

adverse events

Time Frame: Immediately after the surgery

Number of patients with a myocardial infarction, stroke, pulmonary embolism, deep venous thrombosis, sepsis, pneumonia, urinary tract infection, pressure ulcer, or any adverse events.

mortality

Time Frame: 1 year after the surgery

The number of deaths