HIP fracture Accelerated surgical TreaTment And Care tracK (HIP ATTACK) Trial

Completed

Conditions: broken hip
Hip fracture
10005944

Registration Number: NL-OMON48891

Lead Sponsor: Population Health Research Institute

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 35

Inclusion Criteria

1. Age >=45 years
2. Diagnosis of hip fracture during working hours with a low-energy mechanism
(i.e., falling from standing height) requiring surgery

Exclusion Criteria

1. Patients requiring emergent surgery or emergent interventions for another
reason (e.g., subdural hematoma, abdominal pathology requiring urgent
laparotomy, acute limb ischemia, other fractures or trauma requiring emergent
surgery, necrotising fasciitis, coronary revascularization,
pacemaker-implantation)
2. Open hip fracture
3. Bilateral hip fractures
4. Peri-prosthetic fracture
5. Therapeutic anticoagulation not induced by a vitamin K antagonist,
unfractionated heparin (e.g., administration of therapeutic LMWH (>6,000 u/24h)
in the 24 hours prior to enrolment) or intake of any other non-reversible oral
anticoagulant(s) for which there is no reversing agent available
6. Patients on a therapeutic vitamin K antagonist with a history of heparin
induced thrombocytopenia (HIT)
7. Patients refusing participation
8. Patients previously enrolled in the study

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary outcome is to determine the effect of accelerated medical clearance<br /><br>and accelerated surgery compared to standard care on the 90-day risk of the<br /><br>following two co-primary outcomes: all-cause mortality and major perioperative<br /><br>complications (i.e., a composite of mortality, nonfatal myocardial infarction,<br /><br>nonfatal venous thromboembolism, nonfatal pneumonia, nonfatal sepsis, nonfatal<br /><br>stroke, and nonfatal life-threatening and major bleeding) in patients who have<br /><br>suffered a hip fracture.</p><br>

Secondary Outcome Measures