Multicentre, international, parallel group randomized controlled trial to determine whether accelerated surgery for hip fracture in patients with acute myocardial injury is superior to standard care in reducing death at 90 days after randomizatio

Not Applicable

• Conditions: Health Condition 1: S790- Physeal fracture of upper end of femur

• Registration Number: CTRI/2022/08/045084
• Lead Sponsor: Population Health Research Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 1 April 2024

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1) age =45 years;

2) diagnosis of hip fracture during working hours with a low-energy mechanism requiring surgery;

3) troponin elevation on hospital arrival (at least one troponin level from hip fracture occurrence to randomization above the upper limit of normal); and

4) written informed consent.

Exclusion Criteria

1) taking a therapeutic dose of an anticoagulant for which no reversing agent is available;

2) patients on a therapeutic vitamin K antagonist with a history of heparin induced thrombocytopenia (HIT);

3) patients with peri-prosthetic fracture, open fracture or bilateral fractures;

4) patients requiring an emergency surgery for another reason (e.g., subdural hematoma);

5) patients with acute myocardial infarction with a mechanical complication (i.e., acute papillary muscle rupture, ventricular septal defect), ST elevation myocardial infarction, or cardiogenic shock;

6) patients refusing consent; or

7) patients previously enrolled in HIP ATTACK-2.

Study & Design

• Study Type: Interventional
• Study Design: Not specified