Clonidine as an additive to local anaesthetic injections around scalp.
- Conditions
- ASA I and II patients
- Registration Number
- CTRI/2014/10/005151
- Lead Sponsor
- King Edward Memorial Hospital
- Brief Summary
Primary purpose is to study the duration of analgesia and intraoperative haemodynamics after addition of clonidine to scalp block with 0.25% bupivacaine. It is hypothetised that clonidine will prolong the duration of anaesthesia and provide stable intraoperative haemodynamics.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 60
1] 60 ASA I and II patients 2] Age 18yrs to 65 yrs 3] Glasgow coma scale 15/15 4] Patients undergoing supratentorial craniotomies under general anaesthesia.
1] Emergency cases 2] Patients with uncontrolled hypertension 3] Ischaemic heart disease or cardiac arrhythmias 4] Hepatic or renal disease 5] severe pulmonary disease 6] chronic alcoholism and chronic drug abusers 7] History of craniotomy 8] History of drug allergy to local anaesthetics and/or clonidine 9] patients on alpha blockers preoperatively 10] patient refusal.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Duration of postoperative analgesia 24 hours
- Secondary Outcome Measures
Name Time Method Intraoperative haemodynamics Every 5 minutes from skin incision to dura opening and dura closure to skin suturing Intraoperative requirement of fentanyl intraoperative Complications like bradycardia, hypertension etc. intraoperative
Trial Locations
- Locations (1)
GSMC and King Edward Memorial Hospital, Department of anaesthesiology.
🇮🇳(Suburban), MAHARASHTRA, India
GSMC and King Edward Memorial Hospital, Department of anaesthesiology.🇮🇳(Suburban), MAHARASHTRA, IndiaDr Anjana WajekarPrincipal investigator919930104106anjanawajekar@gmail.com