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临床试验/NCT03138590
NCT03138590终止不适用

Investigating Accelerated Learning in Healthy Subjects

The University of Texas at Dallas1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2017年4月4日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
终止
入组人数
20
试验地点
1
主要终点
Associative Memory Assessed by a Verbal Paired-Associate Test

研究概览

简要总结

The purpose of this study is to investigate whether it is possible to accelerate learning and improve associative memory performance in healthy subjects, by applying transcranial Direct Current Stimulation (tDCS) targeting the trigeminal nerve during a verbal paired-associate learning task

详细描述

Associative memory refers to remembering the association between two items, such as a face and a name or a word in English and the same word in another language. It is not only important for learning, but it is also one of the first aspects of memory performance that is impacted by aging and by Alzheimer׳s disease. For decades, neuroscientists have investigated associative learning and memory and ways to accelerate and enhance associative learning and memory.

Transcranial Direct Current stimulation (tDCS) is a non-invasive and painless electrical stimulation technique that has demonstrated to accelerate learning and improve memory in some studies. To investigate whether it is possible to accelerate learning and improve associative memory using tDCS, the performance in a Verbal Paired-Associate memory task of 2 groups will be compared. The first group will get active tDCS during the verbal paired-associate learning task. The second group will get sham tDCS during the verbal paired-associate learning task.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Double (Participant, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Native English Speaker

排除标准

  • •History of severe head injuries, epileptic insults, or heart disease.
  • •Severe psychiatric disorders and severe untreated medical problems
  • •Acquainted with the foreign language used in the learning task
  • •Contraindications for tDCS (e.g. pregnant, implanted devices)

研究组 & 干预措施

Active tDCS

Experimental

Active transcranial Direct Current Stimulation targeting the trigeminal nerve

干预措施: Transcranial Direct Current Stimulation- Neuroconn DC Stimulator PLUS (Device)

Sham tDCS

Sham Comparator

Sham transcranial Direct Current Stimulation targeting the trigeminal nerve

干预措施: Transcranial Direct Current Stimulation- Neuroconn DC Stimulator PLUS (Device)

结局指标

主要结局

Associative Memory Assessed by a Verbal Paired-Associate Test

时间窗: 1 week after stimualtion

Changes in performance in the Verbal Paired-Associate memory task is compared between the 2 groups (1. Active tDCS 2. Sham tDCS) to investigate the influence of tDCS on Associative Memory.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Sven Vanneste

Associate professor

The University of Texas at Dallas

研究点 (1)

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