IRCT20110731007165N7已完成3 期
Effect of intrauterine administration of granulocyte-colony stimulating factor (GCSF) in IVF cycles on the fertility rate of infertile women suffering from moderate to severe endometriosis
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 66
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 40 years（—）
- 性别
- Female
入选标准
- •First time IVF due to infertility
- •Moderate to severe endometriosis (according to laparoscopic criteria, moderate endometriosis was defined as Adhesion affecting Fallopian tubes or ovaries, and severe endometriosis was defined as the involvement of Fallopian tubes, ovaries, and cul-de-sac)
- •Age 18-40 years
- •Fertility due to endometriosis
- •Moderate -to –severe endometriosis was characterized by endometrial glands and stroma at least 5 mm beneath the peritoneum or an ovarian endometriotic cyst (endometrioma)
排除标准
- •Male factor infertility.
- •Evidence of a significant decrease in the ovarian reserve (FSH>11, AMH<0.5, decreased AFC),
- •Endocrine disorders (diabetes, thyroid diseases, hyperprolactinemia, hypothalamic amenorrhea, etc.)
- •, confirmed medical and immunologic diseases (SLE, rheumatoid arthritis, antiphospholipid syndrome, cardiovascular, liver, and renal diseases),
- •and congenital uterine anomalies and uterine cavity disorder (bicornuate uterus, unicornuate uterus, Asherman syndrome, myoma, polyps, etc.).
- •Donation candidates (ovum donation and surrogate utrus) were also excluded from the study
研究者
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