The effect of Granulocyte Colony-Stimulating Factor (G-CSF) on endometrial thickness
Not Applicable
- Conditions
- Infertility and treatment methods.Female infertility
- Registration Number
- IRCT2017030722206N3
- Lead Sponsor
- Vice chancellor for research of Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 80
Inclusion Criteria
Infertile women, Age between 20-45, women are receiving conventional treatment: estradiol valerate , women with normal endometrial thickness (more than 6 mm) for control group and women with endometrial thickness less than 6 mm for intervention group
Exclusion criteria: Presence of Granulocyte colony, stimulating factor (G-CSF) contra-indications including: Sickle cell anemia, Chronic neutropenia, Past history of malignancy, Presence of malignancy, Upper respiratory infections, History of uterine surgery, Renal failure, Azoospermia in patient's husband, Pneumonia, Congenital fructose intolerance, Thyroid diseases , Diabetes, Asherman syndrome
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Endometrial thickness. Timepoint: Before intervention and 72 hours after intervention. Method of measurement: Transvaginal sonography.
- Secondary Outcome Measures
Name Time Method Clinical pregnancy. Timepoint: 3 weeks after positive serum ßhCG. Method of measurement: Vaginal ultrosonography.;Implantation rate. Timepoint: 14 days after embryo transfer. Method of measurement: Measurement of serum ßhCG.