Does Targin provide effective analgesia while reducing ileus in postoperative colorectal and upper gastrointestinal surgery?

• Conditions: Analgesia for post colorectal and upper gastrointestinal surgery; Anaesthesiology - Pain management

• Registration Number: ACTRN12613001197729
• Lead Sponsor: Bay of Plenty District Health Board

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-10-30
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

Having a planned colorectal or upper gastrointestinal surgery
Have good general health as evidenced by medical history. (ASA equal or less than 3)
Have normal renal function with Creatinine Clearance > 60ml/min an CK levels within normal limits
Be willing to comply with all study procedures and be available for the study duration
Women of reproductive potential should not be pregnant or intend becoming pregnant and taking adequate contraception during the treatment period
Provide signed and dated informed consent.

Exclusion Criteria

Taking antidepressants, anticonvulsants, opioids (incuding Tramadol and Codeine)
History of ongoing constipation
Have an allergy to any opioids, paracetamol, NSAIDs or Cox 2 inhibitors
Diabetes Mellitus
Chronic Pain Syndromes
Has been treated with another investigational medication or other intervention (within 30 days of commencing on study drug)
Can not read and write in the English language
Having anything that in the opinion of the investigator, would place the participant at increased risk or preclude the subjects full compliance with or completition of the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified