Topical effect of tarragon oil extract on pain intensity, dryness and physical function of knee joint in patients with chronic osteoarthritis referred to Taleghani Gonbad Kavous Hospital in 1399

Phase 3

Conditions: Chronic osteoarthritis.
Osteoarthritis of knee

Registration Number: IRCT20211203053264N1

Lead Sponsor: Bojnourd University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 90

Inclusion Criteria

Confirmation of osteoarthritis of the knee by an orthopedic specialist
Pain score = 4 at least in the last 3 months based on the VAS scale
People who are able to understand the description and complete the interview
Written and informed consent of the person
Age 30-70 years
No cancer, pregnancy and blood coagulation diseases such as hemophilia
No wound above the knee joint
No signs of acute infection at the knee joint
No serious diseases such as liver disease and kidney failure
No history of gastric ulcer disease, and skin lesions in the knee area
No surgery to replace the knee joint or inject intra-articular steroids 90 days before the study.
Do not suffer from abnormalities related to the lower limbs

Exclusion Criteria

1- Taking oral and topical steroids for 14 days, alcoholism and drug addiction
Patients with radiculopathy and neuropathy, patients with musculoskeletal diseases (including rheumatoid arthritis, septic arthritis, metabolic arthritis, gout and fibromyalgia)
History of allergic reaction to sweet almond oil or tarragon-derived productsUse more than 2 grams per day of acetaminophen or other analgesics such as injectable drugs or other drugs such as glucosamine and chondroitin sulfate.
Hospitalization
Not wanting to continue participating in the study
Travel and leave treatment

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Intensity of pain. Timepoint: One week and three weeks after the intervention. Method of measurement: WOMAC questionnaire and VAS questionnaire.;Joint dryness. Timepoint: One week and three weeks after the intervention. Method of measurement: WOMAC Questionnaire.;Joint physical function. Timepoint: WOMAC Questionnaire. Method of measurement: One week and three weeks after the intervention.

Secondary Outcome Measures