Superiority of Intensity Modulated Radiotherapy in Recurrent T1-2 Nasopharyngeal Carcinoma

Fujian Cancer Hospital1 site in 1 country168 target enrollmentJanuary 1996

ConditionsNasopharyngeal Cancer Recurrent

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Nasopharyngeal Cancer Recurrent
Sponsor: Fujian Cancer Hospital
Enrollment: 168
Locations: 1
Primary Endpoint: all cause mortality
Status: Completed
Last Updated: 12 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The hypothesis of the study is to address the efficacy and toxicity profile of aforementioned four modalities for rT1-2 NPC.

Characters of the patients:

list item one: 168 patients, median age 48 years (range 16-75 years） proven rT1-2 NPC were diagnosed
list item two: Treated with four different irradiation modalities(3D-CRT,IMRT, BT , BT Combined 3D-CRT or IMRT).
list item three: Median time to recurrence was 30 months (range 1-180months). The median follow-up time was 28 months (range, 4-135 months).

Detailed Description

Objectives: Recurrent T1-2 Nasopharyngeal Carcinoma (rT1-2) may be salvaged by 3D - CRT（3D-Conformal Radiotherapy）, IMRT（ Intensity Modulated Radiotherapy）, Brachytherapy (BT), BT combined 3D - CRT or IMRT . The aim of this study is to address the efficacy and toxicity profile of aforementioned four modalities for rT1-2 NPC. Methods and Materials: 168 patients, median age 48 years (range 16-75 years） proven rT1-2 NPC were diagnosed and treated with four different irradiation modalities(3D-CRT,IMRT, BT , BT Combined 3D-CRT or IMRT) . Median time to recurrence was 30 months (range 1-180months). The median follow-up time was 28 months (range, 4-135 months).

Registry

clinicaltrials.gov

Start Date

January 1996

End Date

March 2011

Last Updated

12 years ago

Study Type

Interventional

Study Design

Single Group