Intensity Modulated Radiotherapy in Recurrent T1-2 Nasopharyngeal Carcinoma
- Conditions
- Nasopharyngeal Cancer Recurrent
- Registration Number
- NCT02113423
- Lead Sponsor
- Fujian Cancer Hospital
- Brief Summary
The hypothesis of the study is to address the efficacy and toxicity profile of aforementioned four modalities for rT1-2 NPC.
Characters of the patients:
* list item one: 168 patients, median age 48 years (range 16-75 years） proven rT1-2 NPC were diagnosed
* list item two: Treated with four different irradiation modalities(3D-CRT,IMRT, BT , BT Combined 3D-CRT or IMRT).
* list item three: Median time to recurrence was 30 months (range 1-180months). The median follow-up time was 28 months (range, 4-135 months).
- Detailed Description
Objectives:
Recurrent T1-2 Nasopharyngeal Carcinoma (rT1-2) may be salvaged by 3D - CRT（3D-Conformal Radiotherapy）, IMRT（ Intensity Modulated Radiotherapy）, Brachytherapy (BT), BT combined 3D - CRT or IMRT . The aim of this study is to address the efficacy and toxicity profile of aforementioned four modalities for rT1-2 NPC.
Methods and Materials:
168 patients, median age 48 years (range 16-75 years） proven rT1-2 NPC were diagnosed and treated with four different irradiation modalities(3D-CRT,IMRT, BT , BT Combined 3D-CRT or IMRT) . Median time to recurrence was 30 months (range 1-180months). The median follow-up time was 28 months (range, 4-135 months).
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 168
- recurrent T1-2 nasopharyngeal carcinoma patients
- non recurrent T1-2 nasopharyngeal carcinoma patients
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method all cause mortality thirteen years
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Fujian Cancer Hospital Radiation Oncology Department
🇨🇳Fuzhou, Fujian, China
Fujian Cancer Hospital Radiation Oncology Department🇨🇳Fuzhou, Fujian, China