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Actigraphy as a new objective measure for apathy in schizophrenia

Completed
Conditions
apathy
listlessness
psychosis
10039628
Registration Number
NL-OMON49082
Lead Sponsor
niversitair Medisch Centrum Groningen
Brief Summary

Trial is onging in other countries

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
76
Inclusion Criteria

Patients:
- At least 18 y.o.a.
- Diagnosis schizophrenia
- Maximum score AES (27)
- Stable medication use (at least 4 weeks prior to inclusion)
- Written informed consent
- Participants should have a normal level of exercise tolerance and no physical
handicaps that limit their radius of action
- Participants should have weekends, wherein they are free from work (i.e. do
not have to work weekend shifts), Healthy subjects:
- At least 18 y.o.a.
- Maximum score AES (27)
- Written informed consent
- Participants should have a normal level of exercise tolerance and no physical
handicaps that limit their radius of action
- Participants should have weekends, wherein they are free from work (i.e. do
not have to work weekend shifts)

Exclusion Criteria

Patients:
- An apathy score above 27 on the apathy subscale of the AES-C
- Current disorder of substance abuse (excluding nicotine addiction)
- Insufficient Dutch language abilities, Healthy subjects:
- History of or current psychiatric or neurological illness
- An apathy score above 27 on the apathy subscale of the AES-S
- Insufficient Dutch language abilities

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>The main study parameters are activity level (Acti-meter) and the degree of<br /><br>apathy (AES). </p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Secondary study parameters are negative symptoms, general psychopathology,<br /><br>depression and the ability to experience pleasure (PANSS, SANS, CDSS and TEPS).</p><br>
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