The representation of the sensibility of the breast on the somatosensory cortex using 7 Tesla fMRI: A pilot study

Completed

Conditions: iet van toepassing, onderzoek bij gezonde proefpersonen
Sensibility of the breast
the feeling of the breast

Registration Number: NL-OMON46265

Lead Sponsor: Plastische Chirurgie

Brief Summary: Trial is onging in other countries

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 20

Inclusion Criteria

- Man or woman
- Between 21 and 35 years old
- Healthy; i.e. no comorbidities
- Women: breast size cup B or C
- BMI < 27.0 kg/m2
- Informed consent

Exclusion Criteria

- Any comorbidities
- Previous breast operation of any kind
- Previous allergic reactions to adhesives or plasters
- Any MRI exclusion criteria e.g.:
o (No piercings or other iron materials (except a metal brace behind front teeth)
o Claustrophobia)

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The hemodynamic response after stimulation of the skin of the breast and<br /><br>nipple-areola complex, representing neuronal activity in that region, is<br /><br>measured. Within the somatosensory cortex (S1 and S2), the temporo-spatial<br /><br>brain activity patterns after the various stimulation conditions are assessed,<br /><br>and the representation of the breast on the somatosensory cortex is mapped. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The temporo-spatial brain activity patterns are studied, to assess whether<br /><br>there are differences in representation of the breast on the somatosensory<br /><br>cortex between subjects of the same sex, as well as whether there are<br /><br>sex-specific differences in representation. </p><br>