Fear generalization: a direct replication of Lissek et al. (2010)
- Conditions
- PanicPanic disorder10002861
- Registration Number
- NL-OMON49639
- Lead Sponsor
- niversiteit Utrecht
- Brief Summary
Trial is onging in other countries
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 3
Comparison subjects have to be free of any current or past axis I
psychopathology as assessed by the Structured Clinical Interview for DSM-IV-TR,
Patient Edition (SCID; American Psychiatric Association, 2000). Participants in
the experimental condition have to be free from current major depressive
disorder, a current or past history of bipolar depression, psychosis and
delusional disorders, and they must be diagnosed with a panic disorder. All
participants should be between 18 and 65 years old and should be capable of
making a reasoned review of their interest with regard to the research, i.e.
giving informed consent.
A history of alcohol or substance abuse or dependence (other than nicotine)
within 6 months before study start; current (possible) pregnancy;
cardiovascular problems or disease; trouble seeing (unless corrected by glasses
or contact lenses); trouble hearing (unless corrected by hearing aids); an
electrical implant (such as a pacemaker, ICD or neurostimulator).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Electromyography (EMG) responses and reported risk ratings for each CS and GS.<br /><br>Online risk ratings and reaction time for the risk ratings. Both<br /><br>electromyograph responses and risk ratings will be used to test between-group<br /><br>differences in the course of learning. </p><br>
- Secondary Outcome Measures
Name Time Method <p>A self-report of anxiety levels after the main experiment will be used for<br /><br>testing between group differences. The Panic Disorder Severity Scale (Shear et<br /><br>al. 1997), State-Trait Anxiety Inventory (Spielberger et al. 1983) and Beck<br /><br>Depression Inventory (Beck et al. 1996) will be used to test for between group<br /><br>differences before the beginning of the study.</p><br>