Metacognitive skill training for schizophrenic patients
Not Applicable
Completed
- Conditions
- Mental and Behavioural DisordersSchizophrenia
- Registration Number
- ISRCTN95205723
- Lead Sponsor
- German Research Foundation (DFG)/Federal Ministry of Education and Research (BMBF) (Germany)
- Brief Summary
2014 results in: http://www.ncbi.nlm.nih.gov/pubmed/25103718 2018 results in: http://www.ncbi.nlm.nih.gov/pubmed/29660572
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 150
Inclusion Criteria
1. Patients diagnosed with schizophrenia spectrum disorder
2. Current or prior delusional symptoms
3. Informed consent
4. Clinical stability
Exclusion Criteria
1. Age beyond 65
2. Severe brain damage
3. Intelligence Quotient (IQ) less than 70
4. More than or equal to five for ratings on hostility and non-cooperativeness and more than or equal to six on suspiciousness according to Positive And Negative Symptoms Scale (PANSS) interview
5. Incapacity to give informed consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br> Current primary outcome measure as of 01/11/2012:<br> A delusion score derived from the Positive and Negative Syndrome Scale (PANSS): sum score of items p1 (delusions), p5 (grandiosity) and p6 (suspiciousness)<br><br> Previous primary outcome measures until 01/11/2012:<br> 1. Decline on PANSS positive subscale from T1 (baseline) to T2 (four weeks/assessment immediately after the end of intervention)<br> 2. Conventional algorithm (i.e., sum of PANSS positive items one to seven)<br>
- Secondary Outcome Measures
Name Time Method <br> 1. Improvement of dysfunctional metacognitive biases (i.e., self-serving bias, jumping to conclusions bias, incorrigibility, over-confidence in errors, enhanced need for closure)<br> 2. Subsequent to intervention represents secondary outcome parameter (i.e., difference T1-T2)<br><br> Secondary analyses will include follow-up.<br>