Assessment of Urinary Diversions Outcomes Post Radical Cystectomy in Asyut University Urology Hospital

• Conditions: Bladder Cancer

• Registration Number: NCT04406168
• Lead Sponsor: Assiut University

Brief Summary

Radical cystectomy (RC) for bladder cancer requires reconstruction of the lower urinary tract. Both continent and incontinent diversions are available for urinary reconstruction after RC. Types of urinary diversions include ( ileal conduit, uretero-cutaneous, ureterosigmoidostomy and orthotopic bladder) The decision process is complex and involves consideration of issues related to cancer stage, patient comorbidities, treatment needs, and patient desires related to Quality of life and intraoperative findings. Outcomes of urinary diversions include 1- survival rate (cancer specific or overall survival). 2- Oncological failure (local, distant or LNs). 3- Complications (perioperative, intraoperative or post-operative).

In this study, all these outcomes will be analyzed.

Detailed Description

Not available

Study Timeline

• Status Verified: 2020-05
• Study First Submitted: 2020-05-10
• Study First Submitted QC: 2020-05-27
• Last Update Submitted: 2020-05-27
• Study First Posted: 2020-05-28
• Last Update Posted: 2020-05-28
• Study Start: 2020-06-01
• Primary Completion: 2022-05-01
• Study Completion: 2023-05-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• * All patients underwent radical cystectomy more than 1 year

Exclusion Criteria

• incomplete data
• patients underwent RC outside urology department and presented for treatment of complications.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Rate of patients presented by complications	1 year post operative	such as (change from baseline of the SCR - urinary tract infections - stone formation - stricture at site of anastomosis or stromal stenosis )
Survival rate (overall survival & cancer specific)	1 year post operative	patient live post operative
Rate of patients developed recurrence	1 year post operative	recurrence of cancer

Trial Locations

Locations (1)

Assiut University; 🇪🇬 Assiut, Elgam3a, Egypt