BO and DO in Women With Cystocele Before and After Cystocele Repair

Completed

• Conditions: Bladder Oversensitivity; Detrusor, Overactive
• Interventions: Procedure: Cystocele repair

• Registration Number: NCT04981054
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

The changes of lower urinary tract function after cystocele repair are important for perioperative consultation and management. Thus, the aim of this retrospective study was to evaluate the prevalence of bladder oversensitivity and detrusor overactivity in women with ≥ stage II cystocele and the changes of storage function after cystocele repair.

Detailed Description

Bladder oversensitivity and detrusor overactivity are two important diagnosis of urodynamic study regarding storage function of bladder. Between November 2010 and October 2020, all women with ≥ stage II cystocele who visited the urogynecological department of a medical center for cystocele repair were reviewed. Those women who had complete data of preoperative and postoperative 3-month follow-up urodynamic data were excluded from this study. Bladder oversensitivity was diagnosed if the volume of strong desire was less than 300mL. Detrusor overactivity was defined as the occurrence of involuntary detrusor contractions during filling cytometry.

STATA software was used for statistical analysis. Chi2 test, univariate and multivariable logistic regression tests were used for statistical analysis as appropriate. A p \< 0.05 was considered as statistically significant.

Study Timeline

• Study Start: 2010-11-01
• Primary Completion: 2020-10-31
• Study Completion: 2020-10-31
• Status Verified: 2021-07
• Study First Submitted: 2021-07-20
• Study First Submitted QC: 2021-07-20
• Last Update Submitted: 2021-07-20
• Study First Posted: 2021-07-28
• Last Update Posted: 2021-07-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 483

Inclusion Criteria

• Women with ≥ stage II cystocele
• Received cystocele repair
• Complete urodynamic study before and after surgery

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Exclusion Criteria

• Recurrent cystocele after repairment
• Incomplete data
• Chronic infection

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
cystocele with repairment	Cystocele repair	women with ≥ stage II cystocele who visited the urogynecological department of a medical center for cystocele repair

Primary Outcome Measures

Name	Time	Method
Bladder oversensitivity	November 2010 and October 2020	the volume of strong desire was less than 300mL
Detrusor overactivity	November 2010 and October 2020	the occurrence of involuntary detrusor contractions during filling cytometry

Trial Locations

Locations (1)

National Taiwan University Hospital; 🇨🇳 Taipei, Taiwan