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Clinical Trials/NCT04978714
NCT04978714
Completed
Not Applicable

Prevalence of Urodynamic Stress Incontinence and/or Detrusor Overactivity in Women With Cystocele and the Changes of Continence Function After Cystocele Repair

National Taiwan University Hospital1 site in 1 country483 target enrollmentNovember 1, 2010

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Urodynamic Stress Incontinence
Sponsor
National Taiwan University Hospital
Enrollment
483
Locations
1
Primary Endpoint
Urodynamic stress incontinence
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

The changes of lower urinary tract function after cystocele repair are important for perioperative consultation and management. Thus, the aim of this retrospective study was to evaluate the prevalence of urodynamic stress incontinence and/or detrusor overactivity in women with ≥ stage II cystocele and the changes of incontinence function after cystocele repair.

Detailed Description

Between November 2010 and October 2020, all women with ≥ stage II cystocele who visited the urogynecological department of a medical center for cystocele repair were reviewed. Those women who had complete data of preoperative and postoperative 3-month follow-up urodynamic data were excluded from this study. Urodynamic stress incontinence was diagnosed by the finding of involuntary leakage during filling cystometry or stress urethral pressure profile, associated with increased intra-abdominal pressure, in the absence of a detrusor contraction. Detrusor overactivity was defined as the occurrence of involuntary detrusor contractions during filling cytometry. STATA software was used for statistical analysis. Chi2 test, univariate and multivariable logistic regression tests were used for statistical analysis as appropriate. A p \< 0.05 was considered as statistically significant.

Registry
clinicaltrials.gov
Start Date
November 1, 2010
End Date
October 31, 2020
Last Updated
4 years ago
Study Type
Observational
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Women with ≥ stage II cystocele
  • Received cystocele repair
  • Complete urodynamic study before and after surgery

Exclusion Criteria

  • Incomplete data
  • Chronic infection
  • Recurrent surgery for cystocele

Outcomes

Primary Outcomes

Urodynamic stress incontinence

Time Frame: November 2010 and October 2020

the finding of involuntary leakage during filling cystometry or stress urethral pressure profile, associated with increased intra-abdominal pressure, in the absence of a detrusor contraction

Detrusor overactivity

Time Frame: November 2010 and October 2020

the occurrence of involuntary detrusor contractions during filling cytometry

Study Sites (1)

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