on neurosurgical complications in traumatic neurosurical patients in ICU-its prevalance and effects on the outcome

Not Applicable

Completed

• Conditions: Health Condition 1: null- Traumatic head injury and spinal chord injury patient admitted in IC

• Registration Number: CTRI/2017/11/010508
• Lead Sponsor: Deptof NeuroanaesthesiaAIIMS

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2014-07-15
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 200

Inclusion Criteria

Patients both male and female between age group of 18 to 65 years admitted in ICU

Pre and post operative patients with traumatic brain and spinal chord injury and associated multisystemic involvement admitted in ICU

Variables pertaining to neurological conditions like initial GCS at the time of admission, CT scan findings, ICP monitoring in case of head injury patients, assessment of sensory and motor power especially in spinal chord injury patients was recorded.

Following non-neurological complications parameters were recorded

Respiratory:

Lung infiltration on chest X-ray

PaO2/FiO2 < 200 (Arterial blood gas analysis[ABG])

PaO2/FiO2 200-300(ABG)

Atelectasis on X-ray

Cardiovascular:

Hypotension(Systolic blood pressure[SBP] <90 mmHg),

Hypertension(SBP >160mmHg)

Arrhythmias ( Heart rate[HR] <60beats/min or HR >120beats/min)

Dopamine, dobutamine or norepinephrine-its use and escalation

Infection:

Sepsis (WBC count <4000 /ml or >1100 /ml ,Temp >38.0°C (100.4°F) or <

36°C (96.8°F)

Septic shock (features of sepsis with SBP <90mmHg,HR >90 beats/min

Acute kidney injury (AKI):

Serum creatinine >2mg/dL with or without dialysis

Abdominal complications:

Ileus(absent bowel sound)

Diarrhoea,

Bilirubin levels > 2mg/dL

Aspartate amino transferase (AST) > 60U/L)

Electrolytical complications:

Hyponatremia: (Na level < 130 mmol/L)

Hypernatremia(Na level > 150 mmol/L)

Hyperkalemia(K level >5.0mmol/L)

Hypokalemia(K level <3.5 mmol/L)

Hypocalcemia(Ca level <8 mmol/L)

Bleeding complications:

In terms of requirement of blood and blood products

Criteria for disabilities in case of head injury is the detioration of motor response component of GCS score during ICU stay when compared to the time of ICU admission. In case of cervical injured patients, the disability is any decrease in sensory or motor function developed post ICU admission.

Exclusion Criteria

Patients other then primary brain and spinal chord injury admitted in ICU

Patients with primary brain and spinal chord injury not admitted in ICU

Study & Design

• Study Type: Observational
• Study Design: Not specified