Comparison between metoprolol and pregabalin as premedication in spine surgery

Phase 1

Recruiting

• Conditions: Anaesthesia

• Registration Number: PACTR202102522324854
• Lead Sponsor: Menoufia university hospitals

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-02-08
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

ASA physical status I, aged from 18 to 50 years old scheduled for elective spine fixation surgeries will included In this study

Exclusion Criteria

Any patient who has any of following will be excluded
Hypertension, Diabetes mellitus, hepatic or renal disease, pregnancy, coagulation disorders, Anemia ( HB<10) , Ischaemia heart disease, drug or alcohol abuse, allergy to any of metoprolol or pregabalin, history of beta blockers, calcium channel blocker, tricyclic antidepressants, anticoagulant or clonidine intake

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary aim of this study is to compare between metoprolol and pregabalin as premedication to induce controlled hypotensive anesthesia primarily control heart rate in spine surgery

Secondary Outcome Measures

Name	Time	Method
The secondary aims is to assess field visualization and measure the amount of blood loss in patients of both groups, surgeons satisfaction and also to assess if there are any associated undesirable side effects of metoprolol or pregabalin wil appear