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Piloting Movement-to-Music With Arm-based Sprint-Intensity Interval Training Among Children With Physical Disabilities

Phase 1
Conditions
Cerebral Palsy
Interventions
Behavioral: Sprint-Intensity Interval Training with Telecoaching
Registration Number
NCT05619211
Lead Sponsor
University of Alabama at Birmingham
Brief Summary

This study is investigating the potential effects of a high-intensity home-exercise program among children with cerebral palsy. The program includes rhythmic movements to music that are adapted for wheelchair uses and age-appropriate themes. This project has the potential to address a large knowledge gap in the extant literature, because there are no widely accessible, evidence-based, enjoyable, and age-appropriate modalities for improving cardiovascular fitness or cardiometabolic health among children with disabilities who have mobility disabilities.

Detailed Description

Not available

Recruitment & Eligibility

Status
ENROLLING_BY_INVITATION
Sex
All
Target Recruitment
50
Inclusion Criteria
  • have a medical diagnosis of cerebral palsy, as determined by ICD-10 codes
  • aged 6-17 years old
  • a Gross Motor Function Classification System Level I-III (as determined via participant screening, explained in the protocol section below)
  • medical clearance to participate in high-intensity exercise from a physician (using the attached medical screening form and explained in the intervention safety, monitoring, and response plan)
  • access to a Wi-Fi Internet connection in the home via mobile phone or tablet computer
  • a caregiver who will support and monitor the participant's safety during the intervention and manage the child's exercise schedule.
Exclusion Criteria
  • physically active (defined as >150 minutes per week of self-reported moderate-to-vigorous intensity exercise in a typical week)
  • cannot use their arms for exercise
  • a Gross Motor Function Classification Level of IV-V
  • complete blindness or deafness;
  • Any past history of a contraindication to exercise testing according to American College of Sports Medicine (ACSM) guidelines (Liguori and American College of Sports Medicine, 2020): significant change in the resting electrocardiogram suggesting significant ischemia, myocardial infarction, or other cardiac event, unstable angina, uncontrolled cardiac dysrhythmias causing symptoms or hemodynamic compromise, symptomatic severe aortic stenosis, uncontrolled symptomatic heart failure, pulmonary embolus or pulmonary infarction, myocarditis or pericarditis, aneurysm.
  • pregnant (due to radiation from a Dual Energy X-ray Absorptiometry [DEXA] scan)
  • has not been seen by a physician within the last year
  • uses a g-tube

Eligible caregivers will include parents or legal guardians of the child, who can commit sufficient time to support the child in their roles for the study and communicate in English. Caregivers who have complete blindness or deafness will be excluded from participation.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Movement-to-MusicSprint-Intensity Interval Training with Telecoaching12 weeks of sprint-intensity interval training while following along with YouTube videos that include arm-based routines, with coaching through telecommunications. Participants are instructed to maintain their habitual diet and nutrition patterns
Primary Outcome Measures
NameTimeMethod
Changes in pVO2Week 0, Week 13

peak oxygen consumption (mL/kg-1/min-1) obtained from a graded exercise test on an arm ergometer

Secondary Outcome Measures
NameTimeMethod
changes in fasting low-density lipoproteinWeek 0, Week 13

LDL cholesterol (mg/dL) measured via dried blood spot test

Changes in systolic blood pressureWeek 0, Week 13

systolic blood pressure (mmHg) measured via blood pressure cuff

changes in Hemoglobin A1CWeek 0, Week 13

HbA1C (mmol/mol) measured via dried blood spot test

changes in fasting high-density lipoproteinWeek 0, Week 13

HDL cholesterol (mg/dL) measured via dried blood spot test

changes in total body fatWeek 0, Week 13

body fat in pounds (lbs) measured via DXA scan

changes in fat tissue percentageWeek 0, Week 13

percentage of fat tissue per whole body weight

changes in fasting insulinWeek 0, Week 13

Fasting Insulin (μIU/mL) measured via dried blood spot test

changes in fasting triglyceridesWeek 0, Week 13

Fasting Triglycerides (mg/dL) measured via dried blood spot test

Changes in diastolic blood pressureWeek 0, Week 13

diastolic blood pressure (mmHg) measured via blood pressure cuff

change in body weightWeek 0, Week 13

body weight in pounds (lbs) measured via DXA scan

changes in total lean massWeek 0, Week 13

lean mass in pounds (lbs) measured via DXA scan

changes in C-reactive proteinWeek 0, Week 13

hsCRP (mg/L) measured via dried blood spot test

changes in lean tissue percentageWeek 0, Week 13

percentage of lean tissue per whole body weight

Trial Locations

Locations (1)

Wellness Health And Research Facility (WHARF)

🇺🇸

Homewood, Alabama, United States

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