Muscle Strength Training for Older Adults With Type II Diabetes

Not Applicable

• Conditions: Type 2 Diabetes Mellitus
• Interventions: Behavioral: Muscle Strengthening exercises

• Registration Number: NCT03280758
• Lead Sponsor: The University of Hong Kong

Brief Summary

This randomised controlled trial aims to investigate a resistance training program for improving glycemic control, muscle mass, strength and functional performance in older patients with Type II Diabetes (T2 DM).

60 subjects will be randomly allocated to either a muscle strengthening group or a no exercise control group.

Muscle strengthening group will receive resistance training 3 times per week (1 hour/session).

The control group will not receive any training but can continue usual medical care and daily activities.

Primary outcomes: glycemic control and lipid profile Secondary outcomes: muscle mass and strength, and functional capacity Data will be collected at baseline (pre-test) and after a 4-month intervention (post-test).

Detailed Description

This study aims to investigate a resistance training program for improving glycemic control, muscle mass, strength and functional performance in older patients with Type II Diabetes (T2 DM).

This is a single-blinded, randomized controlled trial. 60 subjects will be randomly allocated to either a muscle strengthening group or a no exercise control group.

Information on demographic characteristics, body composition, muscle strength, functional capacity and glycemic control will be collected at baseline (pre-test) and after a 4-month intervention (post-test). Muscle strengthening group will receive resistance training 3 times per week (1 hour/session).

The control group will not receive any training but can continue usual medical care and daily activities.

Basic Information
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Recruitment & Eligibility
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Study & Design

Study Timeline

• Status Verified: 2017-09
• Study First Submitted: 2017-09-05
• Study First Submitted QC: 2017-09-11
• Last Update Submitted: 2017-09-11
• Study First Posted: 2017-09-12
• Last Update Posted: 2017-09-12
• Study Start: 2017-10-01
• Primary Completion: 2019-01-30
• Study Completion: 2019-08-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• T2 DM
• 60-75 years old
• ability to perform exercise

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Exclusion Criteria

• Advanced hypertension (≥ 160/100 mm Hg)
• severe obesity (BMI ≥ 48kg/m2)
• insulin pump user
• coronary heart disease history
• chronic obstructive pulmonary disease
• advanced neuropathy
• learning or mental disorder, or
• any other diseases that prevent subjects from exercising safely.
• Those who participate in regular resistance or aerobic exercises will also be excluded.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Muscle strengthening group	Muscle Strengthening exercises	Participants will be required to perform muscle strengthening exercises 3 hours per week. Close kinetic chain exercises will be performed progressively according to the ACSM guidelines over the 4-month intervention period. The exercise intervention will be conducted by an experienced sports trainer.

Primary Outcome Measures

Name	Time	Method
Fasting glucose level	4 months
Lipid profiles	4 months	HDL, LDL, Trig

Secondary Outcome Measures

Name	Time	Method
Functional performance	4 months	Walking ability
Muscle strength	4 months	Whole body
Muscle mass	4 months	Whole body