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Clinical Trials/NCT03280758
NCT03280758
Unknown
N/A

Effects of Muscle Strength Training on Glycemic Control, Muscle Mass, Muscle Strength and Functional Capacity in Older Adults With Type II Diabetes: A Randomised Controlled Trial

The University of Hong Kong0 sites60 target enrollmentOctober 1, 2017

Overview

Phase
N/A
Intervention
Not specified
Conditions
Type 2 Diabetes Mellitus
Sponsor
The University of Hong Kong
Enrollment
60
Primary Endpoint
Lipid profiles
Last Updated
8 years ago

Overview

Brief Summary

This randomised controlled trial aims to investigate a resistance training program for improving glycemic control, muscle mass, strength and functional performance in older patients with Type II Diabetes (T2 DM).

60 subjects will be randomly allocated to either a muscle strengthening group or a no exercise control group.

Muscle strengthening group will receive resistance training 3 times per week (1 hour/session).

The control group will not receive any training but can continue usual medical care and daily activities.

Primary outcomes: glycemic control and lipid profile Secondary outcomes: muscle mass and strength, and functional capacity Data will be collected at baseline (pre-test) and after a 4-month intervention (post-test).

Detailed Description

This study aims to investigate a resistance training program for improving glycemic control, muscle mass, strength and functional performance in older patients with Type II Diabetes (T2 DM). This is a single-blinded, randomized controlled trial. 60 subjects will be randomly allocated to either a muscle strengthening group or a no exercise control group. Information on demographic characteristics, body composition, muscle strength, functional capacity and glycemic control will be collected at baseline (pre-test) and after a 4-month intervention (post-test). Muscle strengthening group will receive resistance training 3 times per week (1 hour/session). The control group will not receive any training but can continue usual medical care and daily activities.

Registry
clinicaltrials.gov
Start Date
October 1, 2017
End Date
August 30, 2019
Last Updated
8 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Shirley S.M. Fong

Dr

The University of Hong Kong

Eligibility Criteria

Inclusion Criteria

  • 60-75 years old
  • ability to perform exercise

Exclusion Criteria

  • Advanced hypertension (≥ 160/100 mm Hg)
  • severe obesity (BMI ≥ 48kg/m2)
  • insulin pump user
  • coronary heart disease history
  • chronic obstructive pulmonary disease
  • advanced neuropathy
  • learning or mental disorder, or
  • any other diseases that prevent subjects from exercising safely.
  • Those who participate in regular resistance or aerobic exercises will also be excluded.

Outcomes

Primary Outcomes

Lipid profiles

Time Frame: 4 months

HDL, LDL, Trig

Fasting glucose level

Time Frame: 4 months

Secondary Outcomes

  • Muscle strength(4 months)
  • Muscle mass(4 months)
  • Functional performance(4 months)

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