Evaluation of Ultrasound-Guided Adductor Canal Blockade for Postoperative Analgesia Following Robotic Medial Unicompartmental Knee Replacement
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Verbal Pain Scores at 6 Hours Post Nerve Blockade.
研究概览
简要总结
This study will evaluate the affects of a single injection ultrasound-guided adductor canal block for patients undergoing robotic-assisted (MAKOplasty) medial UKA (unicompartmental knee arthroplasty). Specifically, this study will compare the adequacy of postoperative analgesia provided by the adductor canal block with that provided by single injection lumbar plexus blockade. The working hypothesis is that the analgesia provided by the adductor canal block will be equivalent to the analgesia provided by the lumbar plexus block. The primary outcome will be a comparison of verbal numerical pain scores at rest and with movement over the first 24 hours following nerve blockade.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 18-85
- •Undergoing unilateral robotic-assisted (MAKOplasty) medial compartment knee arthroplasty at Wake Forest University Baptist Medical Center.
- •Must give written informed consent for anesthesia including subarachnoid blockade and peripheral nerve blockade of both the lumbar plexus and adductor canal.
- •Must consent to the performance of a sham block at the site to which they are not randomized.
- •Must also be reliable to give accurate verbal pain scores postoperatively.
排除标准
- •Contraindication to adductor canal blockade or lumbar plexus blockade (including significant coagulation abnormalities)
- •History of opioid addiction or current chronic pain therapy for pain other than at the surgical site that is being treated with high-dose opioids (extended release opioids or > 40mg oxycodone equivalents per day)
- •Allergy to study medications
- •Failure to adequately place either the adductor canal or lumbar plexus blocks.
- •Patients who decline or have a contraindication to subarachnoid blockade will also be excluded from the study.
- •Pregnancy.
研究组 & 干预措施
Adductor canal block
Patients in this arm will receive an adductor canal block prior to undergoing a medial compartment knee arthroplasty.
干预措施: Adductor canal block (Drug)
Lumbar plexus block
Patients in this arm will receive a lumbar plexus block prior to undergoing a medial compartment knee arthroplasty.
干预措施: Lumbar plexus block (Drug)
结局指标
主要结局
Verbal Pain Scores at 6 Hours Post Nerve Blockade.
时间窗: 6 hours post block.
Comparison of verbal numerical pain scores at rest and with movement 6 hours following nerve blockade. The score range is 0-10 with higher scores denoting worse outcomes.
次要结局
- Quadriceps Motor Strength(6 hours)
- Opioid Related Side Effects(6, 12, 18, and 24 hours)
- Opioid Consumption(6, 12, 18, and 24 hours)
- Time to First Analgesic(24 hours)