Early Discharge to Clinic-Based Therapy of Patients Presenting with Decompensated Heart Failure: A Multi-Centre Randomised Controlled Trial Assessing Impact on Hospital Readmission Rates (EDICT-HF Trial)

Dr Ben Costello0 个研究点目标入组 460 人开始时间: 2024年1月8日最近更新: 2024年2月12日

适应症

试验速览

暂无简介。

•Adult patients (>18 years) presenting to Sunshine Hospital / Footscray Hospital emergency department with ADHF
•Patients admitted to an inpatient ward at Sunshine Hospital / Footscray Hospital with ADHF for <48hrs
•Presentation of ADHF will be determined according to clinical presence of at least 1 relevant symptom and sign:
•oSymptoms: Dyspnoea, orthopnoea, oedema
•oSigns: Rales, peripheral oedema, ascites, pulmonary vascular congestion on chest radiography
•Raised B-Type Natriuretic Peptide (BNP) (>30 pmol/L)
•Informed consent is able to be received from participant

•Haemodynamic instability: Systolic blood pressure <90mmHg or >180mmHg or Heart Rate >100 bpm or <60bpm
•Raised oxygen requirements: Oxygen saturation < 93% on Room Air or Respiratory rate >24 breaths/min
•Serum creatinine >250 umol/L +/- estimated glomerular filtration rate <30 ml/min/1.73m2
•Elevated Serum C-Reactive Protein (CRP) >50 mg/L
•Intravenous vasodilatory or ionotropic agent requirement (excluding Digoxin)
•Febrile >38 degrees Celsius or clinical suspicion of infection
•Evidence of consolidation on chest radiography
•Inpatient admission >48hrs
•Meeting Fourth Universal Definition of Myocardial Infarction criteria
•Unstable arrhythmia (ventricular or supraventricular arrhythmia associated with haemodynamic instability or symptoms)
•Unsafe home discharge environment
•Social or language barriers limiting capacity to gain informed consent

发起方

Dr Ben Costello