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临床试验/NL-OMON54488
NL-OMON54488招募中不适用

Imaging Radiotherapy-induced brain injury using advanced MRI and PET, a pilot - Imaging Radiotherapy-induced brain injury using MRI and PET

niversitair Medisch Centrum Groningen0 个研究点目标入组 40 人开始时间: 待定最近更新:

试验速览

阶段
不适用
状态
招募中
入组人数
40

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 至 64(—)

入选标准

  • - adults (>18 years),
  • - referred for treatment of tumours located in nasopharynx, parotids,
  • oropharynx, skull base and sinonasal cavity (under which meningioma, pituitary,
  • chondrosarcoma, chondroma) with radiotherapy (photons or protons), with or
  • without systemic treatment, with a close proximity of 2 cm of the clinical
  • target volume (CTV elective dose) to the brain or brainstem.

排除标准

  • - age <18 years old at baseline;
  • - brain neurological disease other than consequences of head and neck cancer
  • and its treatment (like a stroke);
  • - history of psychiatric disease;
  • - history of chemotherapy or radiotherapy for other tumours;
  • - chronic treatment with verapamil at baseline;
  • - pregnancy;
  • - contradictions for performing MRI, such as non-MRI compatible heart
  • pacemaker, metallic foreign body in the eye, aneurysm clip in the brain or
  • claustrophobic patient;
  • - contrast allergies.
  • - Tumour extension into the brain

研究者

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