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Clinical Trials/NL-OMON24435
NL-OMON24435
Not yet recruiting
Not Applicable

Imaging radiotherapy-induced brain injury using advanced MRI and PET

Medical Imaging Center, UMCG0 sites40 target enrollmentTBD
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ConditionsHead-neck cancer

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Head-neck cancer
Sponsor
Medical Imaging Center, UMCG
Enrollment
40
Status
Not yet recruiting
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Observational non invasive

Investigators

Sponsor
Medical Imaging Center, UMCG

Eligibility Criteria

Inclusion Criteria

  • •?adults (18\-70 years),
  • •?referred for treatment of tumours located in nasopharynx, oropharynx and sinonasal cavity with radiotherapy (photons or protons), with or without systemic treatment, with a close proximity of 1\.5 cm of the clinical target volume (CTV elective dose) to the brain or brainstem.

Exclusion Criteria

  • •?age \<18 or \> 70 years old at baseline;
  • •?brain neurological disease other than consequences of head and neck cancer and its treatment (like a stroke);
  • •?history of psychiatric disease;
  • •?history of chemotherapy or radiotherapy for other tumours;
  • •?chronic treatment with verapamil at baseline;
  • •?pregnancy;
  • •?contradictions for performing MRI, such as non\-MRI compatible heart pacemaker, metallic foreign body in the eye, aneurysm clip in the brain or claustrophobic patient;
  • •?contrast allergies.

Outcomes

Primary Outcomes

Not specified

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