Pilot study on 3D-Ultrasound of Peripheral Nerves

Completed

• Conditions: Nerve Disease; Polyneuropathy; 10034606

• Registration Number: NL-OMON47530
• Lead Sponsor: Sint Elisabeth Ziekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 25

Inclusion Criteria

- A diagnosis of CIDP, MMN, MIDN according to the international guidelines
or
- A diagnosis of axonal polyneuropathy, based on findings on EMG
or
- A diagnosis of NF1 according to the international guidelines, or genetically confirmed diagnosis of NF1
or
- Healthy control: participants without any neuropathic complaints (e.g. sensory loss, loss of strength);and
- Age 18-80

Exclusion Criteria

- Being physically unable to undergo sonography

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Several parameters will be evaluated in this study.<br /><br>- CSA measurements obtained from the images acquired with 3D ultrasound.<br /><br>- The quality of sonographic images of 3D ultrasound over a longer tract will<br /><br>be evaluated semi-quantitatively following earlier published criteria.<br /><br>- 3D reconstruction images (and the possibility of creating them in the three<br /><br>groups of participants).<br /><br>- Volumetric measurement values (and the possibility of obtaining them in the<br /><br>three groups of participants).<br /><br>- Inter-observer variability: the CSA measurements and volumetric measurements<br /><br>obtained by 2 different investigators with 3D ultrasound will be compared. Also<br /><br>the CSA measurements obtained with 3D and 2D ultrasound by one investigator<br /><br>each will be compared.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>NA</p><br>