Variations in the level of blood ketones in patients commenced on a very low-calorie diet before and after having weight loss reduction (bariatric) surgery

Not Applicable

• Conditions: Obesity; Diet and Nutrition - Obesity

• Registration Number: ACTRN12620000885998
• Lead Sponsor: Sydney Local Area Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-09-07
• Last Update Posted: 14 September 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 250

Inclusion Criteria

Consented adult patients who undergo all bariatric surgery at CRGH.
- Bariatric surgery defined as the following procedures: sleeve gastrectomy, single loop gastric bypass and gastric bypass Roux-en-Y
-Prescribed a very low carbohydrate diet (VLCD) commenced 2 weeks before surgery
-Non-diabetics patients
Type 2 diabetes mellitus (T2DM) on any treatment.
- Type 2 diabetes defined according to Australian Diabetes Society criteria: any of the following biochemical evidence of impaired glucose tolerance: HbA1c greater than or equal to 6.5% (48 mmol/mol), fasting glucose greater than or equal to 7.0 mmol/L, random glucose greater than or equal to 11.1 mmol/L, on a 75 g oral glucose tolerance test: fasting glucose greater than or equal to 7.0 mmol/L or 2 hr glucose greater than or equal to 11.1 mmol/L, or being treated for diabetes with any diet, oral hypoglycaemic agents or insulin regimen.

Exclusion Criteria

Patients with Type 1 diabetes mellitus

Study & Design

• Study Type: Observational
• Study Design: Not specified