Preoperative pharmacological intervention for prevention of post operative sore throat and hoarseness.
Not Applicable
- Conditions
- Health Condition 1: R69- Illness, unspecified
- Registration Number
- CTRI/2019/02/017804
- Lead Sponsor
- ilavati Hospital and Research Centre
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1) Age 18-75 yrs
2) Male and female patients undergoing elective surgery under general anaesthesia in supine position needing endotracheal intubation
3) American Society of Anesthesiologists (ASA) physical status I-II patients
4) Duration of surgery between 60 mins and 300 mins
5) Mallampatti classification I & II
Exclusion Criteria
1)Recent history of respiratory tract infection or preoperative sore throat
2)More than one attempt at tracheal intubation
3)Pregnant and lactating females
4)Head and neck surgeries
5)Chronic steroid or NSAID(non steroidal anti inflammatory drugs) therapy
6)Known asthmatic or chronic obstructive pulmonary disease
7)Vulnerable subjects
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Comparison of preoperative nebulised ketamine and intravenous dexamethasone used alone or in combination for the prevention of postoperative sore throat and hoarseness.Timepoint: To compare the incidence and severity of post perative sore throat and hoarseness graded on a four point scale at immediate recovery, 3hrs, 6hrs, 12hrs and 24hrs post operatively <br/ ><br> <br/ ><br>
- Secondary Outcome Measures
Name Time Method To study the incidence of adverse effects such as nausea, vomiting. <br/ ><br> <br/ ><br>Timepoint: Occurance of nausea and vomiting at immediate recovery, 3hrs, 6hrs, 12hrs and 24hrs post operatively . <br/ ><br>