NCT01217983已完成不适用
Utility of Renal Biomarkers in Cirrhotic Patients
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 105
- 试验地点
- 1
- 主要终点
- Early detection of acute kidney injury in hospitalized cirrhotic patients with ascitis using new renal biomarkers
研究概览
简要总结
Evaluation of kidney function is critical in cirrhotic patients as there is a clear relationship between renal failure and prognosis. The investigators hypothesized that in this population new biomarkers of renal function could help in early detection of acute renal failure and in discrimination between renal and pre-renal causes. Finally the investigators hypothesized that such biomarkers could predict short-term outcome in this population.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 18 years
- •Known or suspected cirrhosis
- •Suspected ascitis
- •Informed consent signed
排除标准
- •Proven multifocal hepatocellular carcinoma
- •Acute gastric hemorrhage (active or < 2 weeks)
- •Known end-stage renal disease or on dialysis before admission
- •Recipients of kidney or liver transplants
- •Transferred from another institution
结局指标
主要结局
Early detection of acute kidney injury in hospitalized cirrhotic patients with ascitis using new renal biomarkers
时间窗: 30 days
Acute kidney injury will be defined using RIFLE and AKIN criteria.
次要结局
- Prediction of adverse clinical outcomes (Renal replacement therapy, transfer to ICU, all cause mortality).(30 days)
- Prediction of AKI developement using renal artery resistive indexes.(30 days)
- Discrimination between different type of AKI.(30 days)
研究者
Ponte Belen
Dr
University Hospital, Geneva
研究点 (1)
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