Association Between Vitamin D Deficiency and Preeclampsia: A Case Control Study
Completed
- Conditions
- Pre-Eclampsia
- Registration Number
- NCT02677233
- Lead Sponsor
- Ain Shams Maternity Hospital
- Brief Summary
To find out if lower levels of vitamin D is more prevalent in preeclamptic women
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 90
Inclusion Criteria
- Parity: primigravida.
- Age: 18 - 35 years.
- Singleton pregnancy.
- Gestational age: 36-40 weeks.
- No past history of any medical disorder and with no other medical complications during pregnancy
Exclusion Criteria
- Women with preexisting medical conditions like rheumatoid arthritis, thyroid, hepatic or renal failure, metabolic bone disease, diabetes mellitus, malabsorption and lupus.
- History of intake of medications influencing bone, vitamin D or calcium metabolism e.g. antiepileptic, theophylline, antitubercular drugs in the last 6 months.
- Women with multiple pregnancy.
- Women with congenital fetal malformation.
- Women with known thrombophilia
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method vitamin D level in preeclamptic and non preeclamptic women six months
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link 25-hydroxyvitamin D deficiency to endothelial dysfunction in preeclampsia?
How does vitamin D status compare to sFlt-1/PlGF biomarker ratios in predicting preeclampsia severity?
Are VDR polymorphisms associated with differential risk of preeclampsia in vitamin D-deficient populations?
What evidence supports vitamin D supplementation as adjunctive therapy to antihypertensives in preeclamptic management?
Do calcium or magnesium supplements synergize with vitamin D in preventing preeclampsia, and what clinical trials demonstrate this?