Correlation Between Maternal Vitamin D Level And Preterm Birth
- Conditions
- Preterm BirthPreterm LaborVitamin D Deficiency
- Interventions
- Diagnostic Test: Vitamin D measurement
- Registration Number
- NCT03638037
- Lead Sponsor
- Ain Shams Maternity Hospital
- Brief Summary
Assessment of correlation between vitamin D level and prevalence of preterm births remains limited. The exact role of vitamin D in preterm birth has not yet been clearly defined ,where some studies showed vitamin D deficiency increased the risk of preterm birth while other studies found no correlation. In this study will try to continue research on this subject.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 138
Inclusion Criteria
- Singleton gestation.
- Maternal age: 20-35 years.
Exclusion Criteria
- Multi fetal pregnancy.
- Anatomical or genetic defect of the fetus.
- Iatrogenic preterm delivery.
- Maternal medical disorder e.g diabetes millets (D.M).
- Antepartum hemorrhage.
- Hypertensive disorders.
- Polyhydromins or oligolydromins
- Premature rupture of membranes ± Chorioamnionitis
- Incompetent cervix.
- Post IVF.
- Uterine Fibroid or malformation.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Study Vitamin D measurement 69 women, delivered preterm babies (less than 37weeks). Control Vitamin D measurement 69 women, delivered at term (38-42 weeks) of full tem babies.
- Primary Outcome Measures
Name Time Method proportion of patients with severe vitamin D deficiency 3 months vitamin D deficiency defined as vitamin D level \<10ng/mL
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
How does maternal vitamin D deficiency influence immunomodulatory pathways linked to preterm labor and birth?
What is the comparative effectiveness of vitamin D supplementation versus standard-of-care interventions in preventing preterm birth?
Which biomarkers correlate with maternal vitamin D levels to predict preterm birth risk in NCT03638037?
What adverse outcomes are associated with maternal vitamin D deficiency in preterm labor, and how are they managed?
Are there synergistic effects of vitamin D with other nutrients or hormones in reducing preterm birth risk?
Trial Locations
- Locations (1)
Ain Shams University, Maternity Hospital
🇪🇬Cairo, Egypt
Ain Shams University, Maternity Hospital🇪🇬Cairo, EgyptDina MansourContactDinayahiamansour@hotmail.com