What is the appropriate sleep position for Parkinson's disease patients with orthostatic hypotension in the morning?

Recruiting

• Conditions: PD patient with OH; Orthostatic hypotension, Nocturnal hypertension, Supine hypertension, Parkinson' s disease, Sleeping positions

• Registration Number: TCTR20220621005
• Lead Sponsor: Department of Medicine, Faculty of Medicine, Chulalongkorn University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-06-21
• Study Completion: 2022-06-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

1. patients who have been office BP measurements demonstrating a drop of at least 20 mmHg of SBP or 10 mmHg of DBP after 3 min of standing from a supine position at least two visited at the outpatient clinic, 2. stable dosage of antiparkinsonian and antihypertensive medications at least 4 weeks prior to the study, 3. able to stand at least three minutes for BP measured

Exclusion Criteria

Patients with comorbidities of chronic heart failure, chronic renal failure, amyloidosis, active malignancies, other secondary forms of autonomic diseases, diabetes mellitus or diseases potentially associated with autonomic dysfunction, and parkinsonism plus syndrome

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Magnitude of orthostatic hypotension at the end of intervention 24 hour BP monitoring

Secondary Outcome Measures

Name	Time	Method
nocturnal blood pressure at the end of intervention 24-hour BP monitoring,Symptom of orthostatic hypotension at the end of intervention orthostatic hypotension questionnaire