The effects of high fat meals enriched with n-3 fatty acids on blood pressure at rest & during exercise

Completed

• Conditions: Cardiovascular disease; Circulatory System; Heart disease

• Registration Number: ISRCTN62232400
• Lead Sponsor: King's College London (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-10-27
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 22

Inclusion Criteria

Healthy men, aged 18 - 45 years

Exclusion Criteria

1. Current smokers or those smoked in the past 6 months
2. Consumption of more than a portion of oily fish per week and/or regular fish oil supplementation within the past 3 months
3. Body mass index less than 18.0 and greater than 30 kg/m2
4. Seated blood pressure of or greater than 140/90mmHg
5. Plasma total cholesterol > 7.8 mmol/L;
6. Plasma triacylglycerol (TAG) >3.0 mmol/L;
7.Diabetes mellitus (fasting plasma glucose >7.0 mmol/L)
8. Abnormal haematology or liver function tests
9. Self-reported history of myocardial infarction, angina, venous thrombosis, stroke, cancer
10. Presence of gastrointestinal disorder or use of a drug, which is likely to alter gastrointestinal motility or nutrient absorption
11. Self-reported weekly alcohol intake of > 28 standard units of alcohol (1 unit = 10 mL ethanol)
12. Systematic use of any kind of drug or prescribed blood pressure anti-inflammatory or blood-thinning medication

Study & Design

• Study Type: Interventional
• Study Design: Not specified