An audit to find out about the blood coagulation related problems and epidural catheter (tube inserted in back for pain treatment) practices in a patient after operations.

Not Applicable

Not yet recruiting

• Conditions: Health Condition 1: C40- Malignant neoplasm of bone and articular cartilage of limbsHealth Condition 2: C15-C26- Malignant neoplasms of digestive organs

• Registration Number: CTRI/2021/01/030571
• Lead Sponsor: Tata Memorial Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1) Adult patients ( > 18 years) with a normal preoperative platelet count and coagulation profile.

2)Elective major surgery (Esophagectomy, Gastrectomy, Whipples, Hemipelvectomy, Sacrectomy, Cytoreductive surgery and HIPEC) with major blood loss/massive transfusion

3)ASA grade I, II, III

Exclusion Criteria

1)Preoperative deranged platelet count/coagulation profile

2)Patient on anticoagulant therapy

3)Patient with bleeding disorders

4)Emergency surgeries

5)Paediatric population

6)Hepatectomy (as these patients are being enrolled in another trial)

7)Postoperative epidural catheter insertion

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To identify the percentage of patients with deranged coagulation profile in the postoperative period potentially delaying/ interfering with epidural catheter removalTimepoint: Post operative day1, day 2, day3 and 1 month after removal of Epidural catheter

Secondary Outcome Measures

Name	Time	Method
The average perioperative blood loss in these surgeriesTimepoint: Post operative day1, day 2, day3 and 1 month after removal of Epidural catheter;Epidural catheter duration (days in situ)Timepoint: 1 month after removal of Epidural catheter;Percentage of patients in whom a TEG (viscoelastic testing) was done prior to epidural catheter removalTimepoint: Post operative day1, day 2, day3 and 1 month after removal of Epidural catheter;The percentage of patients requiring Vitamin K and /or blood products (FFP and/or platelets) to correct the derangement prior to catheter removalTimepoint: Post operative day 1, day 2, day 3;The percentage of such patients developing complications related to epidural catheter removal i.e, catheter related infection, epidural hematomaTimepoint: Post operative day1, day 2, day3 and 1 month after removal of Epidural catheter