Venous Disease Thromboembolic and Amyotrophic Lateral Sclerosis
- Conditions
- Lateral Amyotrophic SclerosisVenous Thrombo-embolic Desease
- Registration Number
- NCT04446325
- Lead Sponsor
- University Hospital, Brest
- Brief Summary
Venous thrombo-embolic (VTE) rates could be high in patients with amyotrophic lateral sclerosis (ALS). Indeed, the rate of VTE in this specific population could be 7-fold higher in this population. Predictiv factors of VTE in patients with ALS are mobility reduction and neurological paralysis. However, to our knowledge, medical littérature is poor concerning VTE and ALS association.
Our first aim is to define annual rate of VTE in ALS population.Then we aim to identify predictiv factors of VTE in this specific population. The studied population is Brest universitary hospital cohort of ALS patient included between 2000 and 2019.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 227
- patients with amyotrophic lateral sclerosis defined by revised El Escorial score criteria followed in competence centre of Brest Universitary Hospital during 2000 to 2019
- no consent
- other neuro-degenerativ diseases
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Number of venous thrombo-embolic eventsrate per year in amyotrophic lateral sclerosis patients followed between 2000 and 2019 in Brest universitary hospital 19 years pulmonary embolism and deep venous thrombosis
- Secondary Outcome Measures
Name Time Method Number of predictiv factors of venous thrombo-embolism events in amyotrophic lateral sclerosis population followed in Brest universitary hospital between 2000 and 2019 19 years immobilization, impairment of respiratory function,, mecanical ventilation, denutrition, artificial nutrition
Trial Locations
- Locations (1)
CHRU de Brest
🇫🇷Brest, France