Immune-enhancing Diet Before and After Surgery for better recovery for Patients with Head and Neck Cancers

Phase 2

• Conditions: Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx

• Registration Number: CTRI/2023/12/060411
• Lead Sponsor: TMC Research Administration Council

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 19 December 2023

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1. Treatment naive Patients with Oral Squamous cell carcinoma (OSCC) planned for radical surgery

2. Age = 18 and = 75

3. Patients with American Society of Anesthesiologists (ASA) grades I, II, or III

4. No history of diabetes or if diabetic, HBA1c = 7.5.

5. Liver function tests (ALT, AST, ALP, and bilirubin) within normal limits

6. The baseline BMI should be between 18 to 25.

7. Preoperative albumin level = 3.0

Exclusion Criteria

1. Patients with ASA grade > III

2. Pregnancy

3. Nutritionally challenged patients requiring supplementation pre surgery as decided by the treating physician and dietician.

4. Non-SCC cases

5. Patients undergoing free flap reconstruction.

6. Patients who are undergoing re-exploration

7. Patients undergoing re-surgery for recurrence.

8. Patients who have undergone any prior alternate treatments or post NACT.

9. Patients with metastases.

10. Patients with renal insufficiency were serum creatinine > 2mg/dl.

11. Patients not willing for Omega-3 from fish oil.

Study & Design

• Study Type: Interventional
• Study Design: Not specified