Effect of perioperative immune-enhancing diet in head and neck cancer surgery patients: a randomized controlled trial

Phase 2

Recruiting

• Conditions: Head and neck cancer patients undergoing major surgery; Head and neck cancer, Surgery, Nutrition, Complication, Infection

• Registration Number: TCTR20200624003
• Lead Sponsor: one

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-06-24
• Study Completion: 2020-09-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Head and neck cancer patients undergoing major surgery
Age 18-75 years

Exclusion Criteria

Previous head and neck surgery
Previous head and neck radiation
Poor liver function(Total bilirubin > 3.5 mg/dl)
Poor renal function (Serum creatinine > 2.5 mg/dl)
Underlying immunodeficiency or taking immunosuppressive drug
Allergy to arginine, glutamine,fish oil, or soy protein
Pregnancy or breast feeding

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
serum albumin, prealbumin, transferrin, total lymphocyte count 1st, 7th, and 14th days after the operation Albumin (g/dl), Prealbumin (mg/dl), Transferrin (mg/dl), Total lymphocyte count (cells/mm2)

Secondary Outcome Measures

Name	Time	Method
Surgical site infection rate, length of hospital stay 1 month, until discharge date percent of patients with surgical site infection, days of hospitalization