The effects of a polyphenol-rich blackcurrant drink on markers of the gut-brain axis in healthy females: A randomised double-blind cross-over intervention trial.

niversity of Auckland0 个研究点目标入组 40 人开始时间: 2022年6月16日最近更新: 2022年6月20日

试验速览

暂无简介。

•Females aged between 18-45 years.
•BMI between 18-30 kg/m2.
•Not pregnant, nor intending to become pregnant during the trial.
•Has access to internet and a computer, smart phone, or tablet.
•Agree not to enroll in another interventional clinical research trial 4 weeks prior to and for the duration of the study period
•Understands, and is willing and able to comply with all study procedures
•Willing and able to provide written informed consent

•Treated for anxiety, depression, or psychiatric disorders within the past two years.
•Diagnosed with gastrointestinal disorders (Coeliac disease, ulcerative colitis, Crohn’s disease), or had past major gastrointestinal surgery likely to interfere with study outcomes (e.g., hemi colectomy, ileostomy, colostomy).
•History of neurological disorders (e.g., Epilepsy, Parkinson’s Disease, stroke, serious head trauma), cognitive impairment, cardiovascular diseases or diabetes requiring medication.
•Medication use expected to interfere with normal digestive processes, including proton pump inhibitors, laxatives.
•Antibiotic use in the four weeks prior to the intervention.
•Prebiotic or probiotic supplement use and are not willing to cease intake for four weeks prior to (and duration of) the intervention.
•Herbal extract supplement use expected to interfere with cognition or mood and are not willing to cease use for four weeks prior to (and duration of) the intervention.
•Self-reported alcohol intake exceeding a moderate intake (>15 standard drinks/week).
•Regular use of recreational/illicit drugs
•Sensitivity to the investigational product, or any of the active/inactive ingredients.

发起方

niversity of Auckland