Use of MUAC as Basic Criterion for Admission, Follow-up and Exit From the Ambulatory Nutrition Program

Not Applicable

Completed

• Conditions: Malnutrition
• Interventions: Other: MUAC Program; Other: Standard Program

• Registration Number: NCT03280082
• Lead Sponsor: Epicentre

Brief Summary

The aim of this study is to provide comprehensive documentation of the relevant results and operational implications of this new model using Mid-Upper Arm Circumference (MUAC) as the single anthropometric criterion for admission, monitoring and exit of non- complicated in Niger.

Detailed Description

This is a first operational experiment using Mid-Upper Arm Circumference (MUAC) as the single anthropometric criterion for the admission, monitoring and exit of the management of uncomplicated SAM (Severe Acute Malnutrition) in Niger, specific data as well as data from routine program will be collected to allow comprehensive documentation of all relevant results and operational implications of this new model. The experiment based on the use of the single anthropometric threshold for admission of a Mid-Upper Arm Circumference (MUAC)\<120 mm, which includes both children currently classified as having SAM (currently with PB \<115 mm) and acute malnutrition moderate (MAM, currently with a Mid-Upper Arm Circumference (MUAC)\<125 mm), as well as a follow-up of children with a Mid-Upper Arm Circumference (MUAC)≥ 120 mm, will identify how children respond to treatment and benefit of the spectrum of acute malnutrition.

Study Timeline

• Study First Submitted: 2017-09-07
• Study First Submitted QC: 2017-09-08
• Study First Posted: 2017-09-12
• Study Start: 2018-06-25
• Primary Completion: 2019-02-28
• Study Completion: 2020-12-31
• Status Verified: 2021-02
• Last Update Submitted: 2021-02-09
• Last Update Posted: 2021-02-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 6200

Inclusion Criteria

• All children admitted for non-complicated SAM (Severe Acute Malnutrition) treatment

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Exclusion Criteria

• Children between the ages of 6 and 59 months who were recently excluded from treatment by admission criteria based on MUAC (Sabon Guida site) but were previously eligible for treatment (ie MUAC ≥ 120 and Z score <-3).

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
MUAC Program	MUAC Program	At the CRENAS, MUAC as unique anthropometric criteria for admission, monitoring, and care for the SAM output will be used. The criteria for admission include: * MUAC \<120 mm * Bilateral edema of grade + or ++ The criteria for release of care include: * MUAC ≥ 125 mm at 2 consecutive visits * Minimum stay 3 weeks in the program * Absence of acute medical complications * Absence of edema
Standard Program	Standard Program	Regular screenings in the communities on children between 6 and 59 months of age. Children with MUAC\<125 mm will be referred to Nutrition Centers for admission. The criteria for admission include: * MUAC\<115 mm and/or * Z score \<-3 and /or * Bilateral edema of grade + or ++ The criteria for release of care include: * MUAC ≥ 125 mm at 2 consecutive visits * Minimum stay 3 weeks in the program * Absence of acute medical complications * Absence of edema

Primary Outcome Measures

Name	Time	Method
Nutritional recovery	18 months	Compare the average daily weight gain and the duration of the nutritional treatment per group compare the results of the PB programme, including the overall risk of recovery, transfer, of abandonment, of death, of PB and weight gain and the length of stay by age (6-23 months, compared to 24-59 months), compared the results of the program standard;

Secondary Outcome Measures

Name	Time	Method
Deaths	18 months	Compare the death rate between the two groups
Readmission risks	3 months	Assessment of the risk of readmission 3 months after discharged of the child will be evaluated at 3 months (+/- one week) after discharged of the child

Trial Locations

Locations (1)

CRENAS; 🇳🇪 Madaoua, Niger