Feasibility of Using Physical Activity Monitoring for Enhancing Cognition in Healthy Seniors
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 28
- 试验地点
- 2
- 主要终点
- Cognition
研究概览
简要总结
The goal of this research study is to examine whether an intervention to increase physical activity using a body-worn sensor affects cognitive (thinking) processes.
详细描述
The overall duration of participation in this research study is approximately 4 months. During this time, three study visits will be required. The first visit is for informed consent and screening, the second visit is for baseline fitness and cognitive testing, and the third visit is for follow-up fitness and cognitive testing after a 12-week physical activity monitoring program. Participants will be randomized to one of two study arms, a physical activity monitoring arm and a flexibility and balance arm. Both study arms involve wearing a physical activity sensor and monitoring physical activity for a duration of 12 weeks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 55 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Non-smoking
- •Age between 55-85 years
- •Sedentary status (physically inactive; not participating in at least 30 minutes of moderate intensity physical activity on at least three days per week for at least three months)
- •Generally healthy men and women
- •Living in the greater Boston area
- •Available for the 4 month duration of the study
- •Native-English speaking or fluent in English (must have attended elementary school and higher in English)
排除标准
- •Poor vision that cannot be corrected with glasses or contact lenses
- •Presence of an acute infection
- •Diagnosis of kidney failure
- •Diagnosis of liver disease
- •Diagnosis of thyrotoxicosis/hyperthyroidism
- •Diagnosis of cancer
- •Past or present conditions that affect cognitive functioning:
- •learning disability
- •neurological disorders or conditions (movement disorder, history of head trauma or stroke, epilepsy, etc.)
- •psychiatric disorders or conditions (depression, anxiety disorder, etc.)
- •Past or present conditions that are counter indicators for participation in cardio-respiratory fitness assessment and moderate-intensity physical activity:
- •heart conditions (e.g. heart attack, arrhythmias, etc.)
- •circulatory conditions (e.g. uncontrolled hypertension, leg claudication, high cholesterol, etc.)
- •respiratory conditions (e.g., asthma or lung conditions, such as chronic obstructive pulmonary disease, acute bronchitis, acute common cold, lung cancer, pneumonia, etc.)
- •current musculoskeletal impairments (e.g. fractures, hemiplegia, chronic joint pain, arthritis, osteoporosis, not able to walk comfortably without assistance, etc.)
- •diagnosis of electrolyte disorder or abnormality
- •presence of diabetes mellitus
- •Prescription medication or other drugs that treat heart, lung, or circulatory conditions (e.g. beta blockers, bronchodilators, etc.)
- •Prescription medication or other drugs that affect chemicals in the brain (e.g. antidepressants, anxiolytics, etc.)
- •Implanted medical devices, such as a pacemaker or defibrillator
- •Unavailable for the approx. 4-month duration of the study
结局指标
主要结局
Cognition
时间窗: 80-90 minutes
Change in cognitive task performance post-intervention compared to baseline
Aerobic Fitness
时间窗: 30 minutes
Change aerobic fitness measured with treadmill test post-intervention
次要结局
- Functional fitness: Five Times Sit to Stand(10 min)
- Functional fitness: Timed Get Up and Go(10 min)
- Functional fitness: Flexibility(10 min)
- Physical activity(12 weeks)