ISRCTN15670031
Completed
N/A
A new non-invasive diagnostic method for detection of pathogenic mitochondrial DNA variants using faecal-derived DNA samples
ewcastle upon Tyne Hospitals NHS Foundation Trust0 sites47 target enrollmentMay 16, 2022
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- ewcastle upon Tyne Hospitals NHS Foundation Trust
- Enrollment
- 47
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. A genetically confirmed diagnosis of mitochondrial disease, specifically, the common m.3243A\> G variant.
- •2\. Adults aged \>\=16 years old
- •3\. Paediatrics aged \<16 years old
- •4\. Have ability, in the opinion of the recruiting investigator to undergo all study assessments and investigations.
- •5\. Capable of providing informed consent
Exclusion Criteria
- •1\. Currently have a confirmed bowel obstruction
- •2\. Received surgery on the gastrointestinal tract in last 12 months
- •3\. New drug regime within the 3 months prior to providing a faecal sample
- •4\. Participating in any study that may influence the gastrointestinal tract three months prior to study commencement.
Outcomes
Primary Outcomes
Not specified
Similar Trials
Recruiting
N/A
Development of non-invasive method for the detection of mutated circulating nuclear acidPancreatic cancer Colon cancer Hepatocellar carcinoma Gastric cancer Bile duct cancer Inflammatory bowel disease (Ulcerative colitis, Crohn) Intraductal papillary mucinous neoplasm Autoimmune disease Hepatic/ digestive tract disorderJPRN-UMIN000011814Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.300
Recruiting
N/A
Development of non-invasive diagnostic test based on fetal DNA isolated from maternal blood (NATERA-study)chromosomal aberriationsgenetic defect10083624NL-OMON37477eids Universitair Medisch Centrum300
Completed
N/A
Development of non-invasive methods for diagnosis of asthma and chronic obstructive pulmonary disease (COPD) and for difference between asthma and COPD.Asthma and chronic obstructive pulmonary disease (COPD).JPRN-UMIN000003193Department of Biomedical Laboratory Sciences, Shinshu University School of Health Sciences.90
Recruiting
N/A
Development of non-invasive brief diagnostic marker of nonalcoholic steatohepatitis used by serum free choline scorenonalcoholic steatohepatitisJPRN-UMIN000002623Yokohama-city university200
Completed
N/A
A novel technique for cellular diagnosis utilizing scanning electron microscope.thoracic malignancyJPRN-UMIN000025724ational Cancer Center Hospital100