Atrial Fibrillation and Cancer: a Nationwide French Cohort Study

Active, not recruiting

• Conditions: Cancer; Atrial Fibrillation; Bleeding; Thromboembolism

• Registration Number: NCT05563883
• Lead Sponsor: University Hospital, Caen

Brief Summary

Atrial fibrillation (AF) is a common complication associated with cancer but the risk of AF according to the cancer localization and status as well as the risk of thromboembolisms, bleedings and mortality are poorly known.

The objective of this study is to use a very large French nationwide cohort to adress thèses questions.

Detailed Description

Not available

Study Timeline

• Status Verified: 2022-09
• Study Start: 2022-09-22
• Study First Submitted: 2022-09-24
• Study First Submitted QC: 2022-09-29
• Last Update Submitted: 2022-09-29
• Study First Posted: 2022-10-03
• Last Update Posted: 2022-10-03
• Primary Completion: 2030-01
• Study Completion: 2030-01

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 5000000

Inclusion Criteria

• adult hospitalized patients
• with an ICD-10 code discharge from january 2010 to december 2019 in the French national hospital discharge database (PMSI Programme de Médicalisation des Systèmes d'Information)

Exclusion Criteria

• children

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
cancer	ffrom inclusion in the cohort up to 10 years	occurrence of cancer
atrial fibrillation	from inclusion in the cohort up to 10 years	occurrence of atrial fibrillation

Secondary Outcome Measures

Name	Time	Method
mortality	from inclusion in the cohort up to 10 years	occurrence of mortality
thromboembolism	from inclusion in the cohort up to 10 years	occurrence of thromboembolism
bleeding	from inclusion in the cohort up to 10 years	occurrence of bleeding

Trial Locations

Locations (1)

Service de Cardiologie, Centre Hospitalier Universitaire Trousseau; 🇫🇷 Tours, France