Comparison between the efficacy of dexmedetomidine versus magnesium sulphate as adjuvants to 0.5 percent ropivacaine in axillary brachial plexus block in hand and forearm surgeries
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 81
- 试验地点
- 1
- 主要终点
- To compare the efficacy of dexmedetomidine versus magnesium sulphate as adjuvants to 0.5% ropivacaine in axillary brachial plexus block in hand and forearm surgeries
研究概览
简要总结
It is a prospective , randomized, double blinded comparative study to camparethe efficacy of dexmedetomidine versus magnesium sulphate as adjuvants to 0.5% ropivacaine in axillary brachial plexus block in hand and forearm surgeries.
The parameters that need to be studied are the onset and duration of motor and sensory blockade and the time at which rescue analgesia is required.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator, Outcome Assessor and Date-entry Operator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA grade I and II patients Aged between 18-60 years of either sex.
- •Patients undergoing hand and forearm surgery.
- •Availability of informed consent.
排除标准
- •Patients with ASA physical status III or more.
- •Patients with below 18 years and above 60 years.
- •Patients posted for emergency procedures.
- •Patients with major neurological, cardiac, respiratory, metabolic, renal, hepatic disease or with coagulation abnormalities.
- •Patients with known allergies to the local anaesthetics.
结局指标
主要结局
To compare the efficacy of dexmedetomidine versus magnesium sulphate as adjuvants to 0.5% ropivacaine in axillary brachial plexus block in hand and forearm surgeries
时间窗: The effects of the block needs to be assessed at baseline, after drug administration, after 5,10,15,30,45,60,90,120,150,180 minutes and at the end of surgery
次要结局
- To compare the efficacy of dexmedetomidine versus magnesium sulphate as adjuvants to 0.5% ropivacaine in axillary brachial plexus block in hand & forearm surgeries on the basis of duration of block, bromage scale, VAS score & requirement of any postop analgesia(To assess the duration of analgesia post surgery with the help of VAS score system every 2 hourly till 24 hours post surgery)
研究者
Pratikshya Nath
Dr D.Y. Patil Medical college and hospital and Research center